Tremendous stock with heavy insider buying.

[CHOPTALK]

OPK trading at 3.41.

I have been buying and selling on insider info.
Never seen insider BUYING like I have seen with this stock.

Phillip Frost the CEO of the company and the founder of several successful BIOTECH companies in the past is massively buying shares on the open market in large quantities in OPK.

Frost is a multi-billionaire with a tremendous track record.


OPK has several high dollars approvals about to get approved.

Read up on it. I bought a thousand shares about a month ago in the 3.60's.

 

[CHOPTALK]

lots of buying pressure on this stock right now. The shorts are on the verge of getting squeezed.
Right now is the time to get in.

Trust me on this.

I have spent hundreds of hours learning how to read into insider trading.
Never seen activity like this before.
Something really really big is about to happen with this stock.

 

[Michelangelo]

Good luck Chop. Thanks for the heads up. Watching for now. Don't like the chart.

 

[DeathEatsaCracker]

Chart wouldn't mean much if big news is coming.

Good luck, Chop.

 

[CHOPTALK]

One thing to make clear.

Once insider buying takes place from an insider does not mean that the stock is going to soar overnight like magic.
Insiders have to be real careful when they make large purchases for fear of getting busted for trading on inside info. This means they have to make there moves early. Buying huge blocks of shares the day before big news is very illegal.


If you check the form 4 forms from Phillip Frost over the last 6 months you can see just how aggressive and bullish he has been lately.
Phillip Frost is a legendary investor that is one of the biggest players in the BIO industry. He has been involved in dozens of these companies over the years with a spotless track record. He is one of the Forbes riches people in the world.

This is no pump and dump pink sheet BS that you read about all the time.

He has bought up over 40% of OPK in the last year, and getting more and more aggressive by the day.

He is market buying millions of dollars worth of stock by the day. Just check out the form 4 files on OPK lately.

There is a pretty healthy number of short sellers on this stock that Frost is determined to run off. When this happens it will pop this stock in a large way.

Several huge approvals are on the way.
I think Mr Frost knows one of these things are going to hit big time.

For a company with such a small market cap, this could cause the stock to explode.
Mr Frost did not become one of the 100 most rich people in the world making stupid bets.

Im telling you, of the thousands of stocks I have watched in the last year I have never seen insider activity like this.
Especially from someone so well regarded.

 

[CHOPTALK]

I will give an example of what im talking about.

I bought in a month ago at an average of $3.60.
It is $3.43 right now.
The pop will not be instant, but I do think it will be soon.
The buying by Frost is getting really, really strong.

2 days ago in addition to buying millions of shares on the open market, OPK itself just bought up 2.4 million of its own shares.

Everyone on the inside is very bullish right now, and the shorts are starting to get nervous.
Some of them are already covering there positions.

Either something really big is about to happen, or a lot of smart people who normally do not make bad decisions are going to be fooled.

I will put my money on the smart people.

 

[CHOPTALK]

Before I paste the story im about to paste below let me state that what im about to post has absolutely ZERO to do with why I buy stock.
I buy and sell everything I buy and sell 100% due to insider trading. I have learned that I will never know as much as they know so I have learned how to follow the smart people without asking any questions.

I did not even know what OPK was before I bought it.

It is easier for me to learn how to find out how to follow the insiders then it is for me to learn how to buy and sell based on fundamentals of a stock.

But for those that need to know the fundamentals I will post some info I found on whats in the OPK pipeline.






According to the presentation at Jefferies and the Annual Meeting this month, the No.1, at present, seems to be its Molecular Diagnostic and its innovative platform technology for the discovery of disease-specific antibodies.

They have evidence of a highly reliable, commercially viable blood test for Alheimers' Disease, that is able to distinguish between AD and certain other dementias.
The preliminary results indicate a high sensitivity and the test is able to detect early stage Alzheimer's.
They expect that part of the R&D will be COMPLETED LATE THIS SUMMER and they are ALREADY PLANNING FOR LAUNCHING that product.

The LUNG and PANCREATIC CANCER markers are undergoing validation trials and they expect that R&D will be complete by the 4thQ in 2012.
Those blood tests for Pancreatic Ca and NSCLC are also some very important IRONS on the FIRE.
An early diagnosis and treatment can make a BIG DIFFERENCE in the final outcome on those patients, as well as in other Cas, like in Ovarian Ca, which often times are diagnosed too late, because of the somewhat insidious onset.
In that respect, another important IRON on the FIRE is the potential THERAPEUTIC APPLICATIONS once you have identified the 'surrogate antigens', and the "proof of concept" is their research on Pemphigus.
(Remember that P.Frost is a Dermatologist.

And another important IRON on the FIRE is CURNA, which was just acquired three months ago,for $10M.
CURNA had an important place in OPKO's, last presentation, since its research also seems to have very good potential.

And still another IRON on the FIRE is Rolapitant, that at the JP Morgan presentation in January, was listed in first place.
OPKO already has had a good payback on the 2M that it paid Schering-Plough for Rolapitant.
It has already out-licensed it to Tesaro, and is expected to get $121M in payments as well as double digit royalty payments on sales and it also got 10% of Tesaro's stock.
OPKO won't have any further expenses on Rolapitant's development, since Tesaro will be paying those.
Rolapitant patent has exclusivity for 15 years.
The drug has no significant drug interactions and a single dose has a positive effect up to 5 days.
Those seem to be big advantages, especially for patients receiving chemotherapy.
There are still more IRONS on the FIRE, like the flu vaccine, the Chilean and Mexican companies, and its pulmonary products:
OPK-0018 which is its lead compound for Asthma & COPD. It is a heparin-derived sulfated disaccharide with a novel mechanism of action and no anti-coagulant effects.
The human feasibility study for asthma has been successfully completed.
It is effective orally or by inhalers/nebulizers.
The Asthma /COPD market was estimated around $26 billion in 2009.
Its SCH 900978 for Chronic Cough has completed the PII and no safety issues have been identified. It has a patent exclusivity for the next 16+ years.
And then the " other investments" :
CoCrystal Discovery, a16% equity interest
It has a new approach to develop broad spectrum anti-viral drugs.
Sorrento Sorrento Therapeutics, a 23% equity interest
It has a new technology to produce human monoclonal antibodies libraries thatreportedly are more complete and more efficient.
Fabrus , a 13% equity interest
It ahs technology to identify therapeutic antibody targets.
Tesaro, a 6% or 10% equity interest, as mentioned with the Rolapitant Iron.

And then there are OPKO's Ophthalmic products, that still remain important,but they are not their main focus.
That's one item that irritates the shorts that keep LIVING in the PAST.
That will be the subject of the next note.

 

[DeathEatsaCracker]

I buy and sell everything I buy and sell 100% due to insider trading. I have learned that I will never know as much as they know so I have learned how to follow the smart people without asking any questions.

Where do you get this info?

 

[SmallDaddy]

Most investment sites have that info. But there is like 1-3 month lag time tho

 

[CHOPTALK]

Less then 48 hours is the lag time, and often the very next day.
It is an SEC rule.

Yes the info is easy to find. You can find it on SEC's website or yahoo and finviz.com
There is more to just reading inside trades. You have to know WHY the trade was made, and what kind of trade.
Exercising options do not count.
You need to learn the motive behind the purchase. You need to learn the history of the insider thats making the purchase.
Its not as simple as just reading the form 4's, but is very rewarding.

Most investment sites have that info. But there is like 1-3 month lag time tho

 

[CHOPTALK]

Jun 22, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.38 - $3.44 per share. 171,0002
Jun 17, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.28 - $3.31 per share. 165,0002
Jun 16, 2011 UPPALURI SUBBARAO V
Officer
1,000 Indirect Purchase at $3.41 per share. 3,410
Jun 16, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.37 - $3.45 per share. 171,0002
Jun 15, 2011 LOGAL ADAM
Officer
50,000 Direct Option Exercise at $0.56 per share. 28,000
Jun 15, 2011 LOGAL ADAM
Officer
50,000 Direct Sale at $3.40 per share. 170,000
Jun 15, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.40 - $3.44 per share. 171,0002
Jun 14, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.42 - $3.49 per share. 173,0002
Jun 13, 2011 PAGANELLI JOHN A
Director
10,000 Direct Purchase at $3.44 per share. 34,400
Jun 13, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.36 - $3.46 per share. 171,0002
Jun 10, 2011 FROST PHILLIP MD ET AL
Officer
20,000 Indirect Purchase at $3.43 - $3.45 per share. 69,0002
Jun 9, 2011 FROST PHILLIP MD ET AL
Officer
88,959 Indirect Purchase at $3.41 - $3.47 per share. 306,0002
Jun 8, 2011 FROST PHILLIP MD ET AL
Officer
30,000 Indirect Purchase at $3.52 - $3.54 per share. 106,0002
Jun 3, 2011 FROST PHILLIP MD ET AL
Officer
15,000 Indirect Purchase at $3.54 - $3.57 per share. 53,0002
Jun 1, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.56 - $3.69 per share. 181,0002
May 31, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.68 - $3.77 per share. 186,0002
May 27, 2011 FROST PHILLIP MD ET AL
Officer
10,000 Indirect Purchase at $3.75 - $3.77 per share. 38,0002
May 24, 2011 FROST PHILLIP MD ET AL
Officer
10,000 Indirect Purchase at $3.70 - $3.72 per share. 37,0002
May 19, 2011 FROST PHILLIP MD ET AL
Officer
35,454 Indirect Purchase at $3.80 per share. 134,725
May 17, 2011 FROST PHILLIP MD ET AL
Officer
15,000 Indirect Purchase at $3.66 - $3.68 per share. 55,0002
May 16, 2011 FROST PHILLIP MD ET AL
Officer
20,000 Indirect Purchase at $3.66 - $3.68 per share. 73,0002
May 13, 2011 FROST PHILLIP MD ET AL
Officer
15,000 Indirect Purchase at $3.70 - $3.74 per share. 56,0002
May 11, 2011 FROST PHILLIP MD ET AL
Officer
15,000 Indirect Purchase at $3.76 - $3.82 per share. 57,0002
May 6, 2011 FROST PHILLIP MD ET AL
Officer
15,000 Indirect Purchase at $3.73 - $3.75 per share. 56,0002
May 5, 2011 FROST PHILLIP MD ET AL
Officer
20,000 Indirect Purchase at $3.69 - $3.76 per share. 75,0002
May 4, 2011 FROST PHILLIP MD ET AL
Officer
20,000 Indirect Purchase at $3.78 - $3.81 per share. 76,0002
May 3, 2011 FROST PHILLIP MD ET AL
Officer
20,000 Indirect Purchase at $3.79 - $3.85 per share. 76,0002
Apr 21, 2011 FROST PHILLIP MD ET AL
Officer
20,000 Indirect Purchase at $3.73 - $3.75 per share. 75,0002
Apr 18, 2011 FROST PHILLIP MD ET AL
Officer
25,000 Indirect Purchase at $3.75 - $3.84 per share. 95,0002
Apr 13, 2011 FROST PHILLIP MD ET AL
Officer
10,000 Indirect Purchase at $3.64 - $3.66 per share. 37,0002
Apr 11, 2011 FROST PHILLIP MD ET AL
Officer
15,000 Indirect Purchase at $3.68 - $3.74 per share. 56,0002
Apr 8, 2011 FROST PHILLIP MD ET AL
Officer
10,000 Indirect Purchase at $3.76 - $3.78 per share. 38,0002
Apr 6, 2011 FROST PHILLIP MD ET AL
Officer
10,000 Indirect Purchase at $3.78 per share. 37,800
Apr 1, 2011 FROST PHILLIP MD ET AL
Officer
15,000 Indirect Purchase at $3.71 - $3.76 per share. 56,0002
Mar 31, 2011 FROST PHILLIP MD ET AL
Officer
15,000 Indirect Purchase at $3.73 - $3.75 per share. 56,0002
Mar 30, 2011 FROST PHILLIP MD ET AL
Officer
10,000 Indirect Purchase at $3.78 - $3.82 per share. 38,0002
Mar 28, 2011 FROST PHILLIP MD ET AL
Officer
10,000 Indirect Purchase at $3.75 - $3.76 per share. 38,0002
Mar 23, 2011 FROST PHILLIP MD ET AL
Officer
15,000 Indirect Purchase at $3.65 - $3.84 per share. 56,0002
Mar 22, 2011 FROST PHILLIP MD ET AL
Officer
25,000 Indirect Purchase at $3.59 - $3.73 per share. 92,0002
Mar 18, 2011 FROST PHILLIP MD ET AL
Officer
25,000 Indirect Purchase at $3.65 - $3.67 per share. 92,0002
Mar 16, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.61 - $3.69 per share. 183,0002
Mar 15, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.67 - $3.74 per share. 185,0002
Mar 14, 2011 FROST PHILLIP MD ET AL
Officer
50,000 Indirect Purchase at $3.65 - $3.8 per share. 186,0002
Mar 11, 2011 FROST PHILLIP MD ET AL
Officer
100,000 Indirect Purchase at $3.66 - $3.75 per share. 371,0002
Mar 10, 2011 FROST PHILLIP MD ET AL
Officer
150,000 Indirect Purchase at $3.45 - $3.6 per share. 529,0002
Mar 9, 2011 HSIAO JANE PH D
Officer
533,000 Indirect Acquisition (Non Open Market) at $3.75 per share. 1,998,750
Mar 9, 2011 FROST PHILLIP MD ET AL
Officer
3,200,000 Indirect Acquisition (Non Open Market) at $3.75 per share. 12,000,000
Mar 9, 2011 FROST PHILLIP MD ET AL
Officer
900,000 Indirect Purchase at $3.53 - $3.7 per share. 3,254,0002
Feb 22, 2011 FROST PHILLIP MD ET AL
Officer
30,000 Indirect Purchase at $4.35 - $4.49 per share. 133,0002
Jan 21, 2011 HSIAO JANE PH D
Officer
200,000 Indirect Purchase at $3.55 per share. 710,000
Jan 21, 2011 FROST PHILLIP MD ET AL
Officer
1,158,000 Indirect Purchase at $3.45 - $3.59 per share. 4,076,0002
Jan 19, 2011 FROST PHILLIP MD ET AL
Officer
20,000 Indirect Purchase at $3.54 - $3.82 per share. 74,0

 

[mickj]

Yahoo said there's been insider buying since 07' with this company.

 

[CHOPTALK]

Yahoo said there's been insider buying since 07' with this company.

Thats why you have to learn what kind of insider buying is important.

I will give a great example. Almost every company buys shares of its own stock on a weekly basis to put in employees retirement plans. Every employee has stock options at most companies.

Im not talking about that kind of insider trading.

Im also not talking about activating options.

Im talking open market personal stock purchases.

And who is doing it, and how much, and the track record of who is buying and when.

With all that combined together I challenge anyone to find a CEO more bullish on its companies stock then Phillip Frost.


The last time I found a company with even close to the same type buying was about 3 months ago. Stock symbol HOTT. Bought at 4.75 and sold at 7.00 in less then 3 months.


I expect OPK to do even better.

 

[gmenknicks]

chop

been following your posts about OPK. can i PM you about this?

 

[CHOPTALK]

anyone can PM me about anything

You are from Flordia.

I more then welcome your post.

 

[TheWolf]

BOL Chop. Hope it works out for ya.

 

[CHOPTALK]

From $3.41 to $3.69 in the 3 trading days since I started this thread.

bout to break thru large by every indication I go by.
Just too many smart people betting on this thing.
People that dont lose bets.

 

[CHOPTALK]

From 3.41 to 3.81 in one week of trading
Stock has done nothing but go up since the thread started.

Major movement is on the way.

We are just getting started here.

Too much insider trading for it not to.

 

[gmenknicks]

great eye chop..im riding this with ya

 

[CHOPTALK]

Phillip Frost for the 1st time in almost a year has been real quiet with his buy orders the last 10 trading days.

This is a textbook sign that something really big is right around the corner.

He wanted to get all his chips in before the big news to avoid any insider trading problems.
Because once he knows something thats not public and trades on it blatantly he could be subject to severe SEC problems.

If you were to ever see a textbook example of bullish insider trading and then a quiet period this is the stock.

We are up to 3.90 now from 3.41 in less then 10 trading days.

The buying pressure is strong.
The insiders are positioned, and the shorts are on the verge of getting runoff.